Is it possible to reverse fatty liver disease with weight loss medications?
According to research, persons with liver disease may benefit greatly from drugs often used to treat diabetes and obesity.
Fatty liver is typically viewed as a sneaky ailment, it can start with barely detectable signs, but if left untreated, it can wreak havoc on your health.
Excess fat builds up in your liver cells, potentially leading to inflammation, damage, and even cirrhosis over time. The good news is that, with a few easy lifestyle changes, it can frequently be reversed.
But according to a recent study in the New England Journal of Medicine, drugs that are frequently prescribed for obesity and diabetes may also be very helpful for liver disease patients.
According to a recent study, semaglutide, which is marketed under the names Wegovy and Ozempic, corrected fatty liver disease and decreased inflammation in almost two out of three participants when a 2.4 mg weekly dose was taken for a year and a half. MASH, a form of fatty liver disease associated with diabetes and obesity, was found to respond well to the treatment.
A decrease in hepatic fibrosis, or liver scarring, was also observed in about one in three patients.
The side effects of semaglutide medication, such as nausea, vomiting, diarrhea, constipation, and weight loss, have not changed in the interim. Thyroid cancer, pancreatic inflammation, and stomach paralysis are serious adverse effects.
What is MAFLD?
Previously known as Non-Alcoholic Fatty Liver Disease, Metabolic Dysfunction-Associated Steatotic Liver Disease (MAFLD) is a chronic illness characterized by an excessive accumulation of liver fat. Inflammation, liver damage, and possibly liver cancer can result from this accumulation of fat. It is believed that between 9% and 32% of people in India suffer from MAFLD.
Semaglutide belongs to a class of drugs known as GLP-1 receptor agonists. These medications mimic the actions of particular gut hormones to increase insulin production, decrease glucagon release (which causes the liver to produce glucose), and decrease appetite by delaying digestion.
The medication is intended for those who cannot exercise or who cannot lose weight with diet and exercise.
Excess fat builds up in your liver cells, potentially leading to inflammation, damage, and even cirrhosis over time. The good news is that, with a few easy lifestyle changes, it can frequently be reversed.
But according to a recent study in the New England Journal of Medicine, drugs that are frequently prescribed for obesity and diabetes may also be very helpful for liver disease patients.
According to a recent study, semaglutide, which is marketed under the names Wegovy and Ozempic, corrected fatty liver disease and decreased inflammation in almost two out of three participants when a 2.4 mg weekly dose was taken for a year and a half. MASH, a form of fatty liver disease associated with diabetes and obesity, was found to respond well to the treatment.
A decrease in hepatic fibrosis, or liver scarring, was also observed in about one in three patients.
The side effects of semaglutide medication, such as nausea, vomiting, diarrhea, constipation, and weight loss, have not changed in the interim. Thyroid cancer, pancreatic inflammation, and stomach paralysis are serious adverse effects.
What is MAFLD?
Previously known as Non-Alcoholic Fatty Liver Disease, Metabolic Dysfunction-Associated Steatotic Liver Disease (MAFLD) is a chronic illness characterized by an excessive accumulation of liver fat. Inflammation, liver damage, and possibly liver cancer can result from this accumulation of fat. It is believed that between 9% and 32% of people in India suffer from MAFLD.
Semaglutide belongs to a class of drugs known as GLP-1 receptor agonists. These medications mimic the actions of particular gut hormones to increase insulin production, decrease glucagon release (which causes the liver to produce glucose), and decrease appetite by delaying digestion.
The medication is intended for those who cannot exercise or who cannot lose weight with diet and exercise.
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